Henceforward the last horn of the Goat continued mighty under the Romans, till the reign of Constantine the great and his sons: and then by the division of the Roman Empire between the Greek and Latin Emperors, it separated from the Latins, and became the Greek Empire alone, but yet under the dominion of a Roman family; and at present it is mighty under the dominion of the Turks.
This last horn is by some taken for Antiochus Epiphanes, but not very judiciously. A horn of a Beast is never taken for a single person: it always signifies a new kingdom, and the kingdom of Antiochus was an old one.
Antiochus reigned over one of the four horns, and the little horn was a fifth under its proper kings. This horn was at first a little one, and waxed exceeding great, but so did not Antiochus. His kingdom on the contrary was weak, and tributary to the Romans, and he did not enlarge it. The horn was a King of fierce countenance, and destroyed wonderfully, and prospered and practised; that is, he prospered in his practices against the holy people: but Antiochus was frighted out of Egypt by a mere message of the Romans, and afterwards routed and baffled by the Jews. The horn was mighty by another’s power, Antiochus acted by his own. The horn stood up against the Prince of the Host of heaven, the Prince of Princes; and this is the character not of Antiochus but of Antichrist. The horn cast down the Sanctuary to the ground, and so did not Antiochus; he left it standing. The Sanctuary and Host were trampled under foot 2300 days; and in Daniel’s Prophecies, days are put for years: but the profanation of the Temple in the reign of Antiochus did not last so many natural days.These were to last till the time of the end, till the last end of the indignation against the Jews; and this indignation is not yet at an end. They were to last till the Sanctuary which had been cast down should be cleansed; and the Sanctuary is not yet cleansed.